"Dodge carbohydrates and eat salads and vegetables instead, as the body can break them down quicker and gain energy. Then go for a walk, even if it is only for 10 minutes around the block. Sitting statically makes the blood pool around your ankles. You need to get it circulating again," says Shah.

Kathleen Hall of The Stress Institute and Mindful Living Network offers the S.E.L.F care route to blissful travel.

S - Serenity. Reacting to every obstacle will raise your blood pressure and heart rate. Surrender to your travel and treat it as a classroom (learning experience), not a prison (punishment).

E - Exercise. Exercising releases endorphins that reduces your stress response. Plan for a quick 15 minutes on the treadmill or a couple quick laps in the pool before breakfast.

L - Love. Traveling is stressful, so take tools to comfort yourself on the plane and in your travels. It may be your favorite blanket, pillow or music

F - Food. Eat foods that are high in omega 3 and B6 / B. Try a tuna sandwich or banana. Avoid eating fatty, greasy foods, which can make you feel more anxious.

But for Margolis, the real key is to switch from thinking just about work to incorporating wider interests into your trip. She also recommends common courtesy as a sure-fire way to lower stress levels.

"Be nice! It's amazing what the power of a 'Good Morning' to a hotel desk clerk can mean as you walk by each morning," she says. "These people remember the friendly folks and often go out of their way to enhance our travel experience just by being nice in return."