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ET's JANN CARL was on the set of "Brothers & Sisters" for the interview that everyone wants -- and only ET has: ROB LOWE speaking for the first time about the former nanny who is alleging that he sexually harassed her.

"We live in a time where anybody can say anything about anybody," Rob tells Jann. "You want to defend your family! Now it's in the court system and potentially a criminal investigation."

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