When Manuel Reyna developed a deadly kidney disease, his sister, Florinda Gotcher, didn't hesitate to give him one of her kidneys. When she found out they were a match, she cried.

"She was so happy," remembers Gotcher's daughter, Melinda Williams. "She was overwhelmed that she was able to save her brother's life."

Williams said her mother didn't worry about the risks of surgery. Statistically, kidney donor surgery is considered to be very safe: in 2010, the year before Gotcher's surgery, 6,276 people donated a kidney, and none of them died within 30 days of the surgery.

Her laparoscopic surgery went well, but about 30 minutes afterwards in the recovery room, she took a mysterious turn for the worse.

"She just took a deep breath and her eyes got real huge and then she fell back down and started breathing really, really bad," Williams says.

Surgeons at University Medical Center in Lubbock, Texas, rushed Gotcher back into the operating room. Once they opened her up again, they saw something horrible had happened: there was a pool of blood in her abdomen. Gotcher, 41 and the mother of four, had died from a massive and sudden bleed.

"My world just fell apart and my heart was torn to pieces," Williams says of her mother's sudden death. "They told us, 'We couldn't save her. Sorry, we did everything we possibly could, but there's nothing we could do.'"

No specific warning on surgical device

Williams would later learn her mother's death wasn't a freak accident. It was actually completely preventable.

To remove a kidney for donation, surgeons have to cut the renal artery. They then have to close it back up again, or the patient would bleed to death.

There are various ways to close the artery. Many surgeons use staples, but some use tiny surgical clips to hold it closed.

These clips are considered safe to use in many types of surgeries, but not laparoscopic kidney donor surgeries. In donors surgeries, surgeons leave only a tiny stump of renal artery, and the clips can slip off. That's what happened to Gotcher: when doctors opened her back up, they found the clips had slipped off the stump and were floating in a pool of blood in her abdomen.

Before Gotcher's death, four other kidney donors had died when these clips were used: one in 2001 in the United States, one each in Singapore and Israel in 2005, and another in the U.S. in 2008. At least 12 others have suffered injuries.

Starting in 2004, transplant surgeons, such as Dr. Amy Friedman, began raising concerns about using clips in kidney donors, sending letters to the U.S. Food and Drug Administration and making presentations at transplant conferences and publishing articles in medical journals.

When she heard about Gotcher's death in 2011, Friedman said she was "devastated."

"We were just in shock and deep sorrow to learn that our actions thus far and our efforts to try to stop the practice had been ineffective," says Friedman, director of transplant services at Upstate Medical University in Syracuse, N.Y.

Friedman said there should be a warning label right on the clips.

"I think it would be great to say, 'Don't use on a kidney donor,'" she says.

The clip packaging does have a warning symbol advising doctors to look at the instructions that come with a separate tool used to apply the clips. The instructions, which are typically not kept in operating rooms, state the clips should not be used on kidney donors.

"It's meaningless"