Police say four masked and armed suspects entered the McDonald's restaurant on Reid Street just before midnight Tuesday and shot an employee, according to the Palatka Police Department.
The victim was taken to Putnam Community Medical Center, then airlifted to UF Health in Gainesville. Police did not release his name or know his condition.
Police say there were no customers in the restaurant at the time.
Employees say all four had guns and described the scene as "chaos."
"Witnesses say they were in and out so quick, they didn't say anything to anybody," Palatka Crime Scene Investigator David Parsons said.
The suspects ran east on Reid Street after the shooting and were still at large Wednesday afternoon.
Anyone with information about the robbery or the robbers is asked to contact the Palatka Police at 386-329-0115 or 386-329-0800. Information can also be left on the Palatka Police Department tip line at 386-329-0170.