Two people were killed early Thursday in a fiery head-on, wrong-way crash on State Road 408 in Orlando, forcing officials to close the roadway for several hours.

The crash occurred around 3:40 a.m. on eastbound S.R. 408 near the Hiawassee Road toll plaza.

According to the Florida Highway Patorl, a black 2000 Hyundai Elantra driven by a man was headed westbound in the eastbound lanes of S.R. 408 and crashed into a red 2009 Toyota Corolla driven by a 66-year-old Oakland, Fla., man.  Both drivers, whose names have not been released, were killed in the crash.

A 2001 Jeep Grand Cherokee driven by Robert Lee Gendron, 47, of Clermont, was also involved in the crash, the FHP said.  He was taken to Orlando Regional Medical Center with minor injuries.

Troopers said they're looking for anyone that may have seen the Elantra driving westbound in the eastbound lanes prior to the crash.

Eastbound S.R. 408 was closed for about six hours at Good Homes Road. 

The crash remains under investigation.