March 2010 - Undergoes gall bladder and intestinal surgery in Germany.
May 2010 - Requests Egypt's parliament extend emergency law in the country for two more years until May 31, 2012. The request is granted. The country is under the same martial law that has been in place since October 1981 when Sadat was assassinated.
January 2011 - Rioting in Cairo and other cities over poverty, unemployment and repression in Egypt. Protestors call for Mubarak to step down.
January 29, 2011 - Just after midnight Cairo time, Mubarak addresses the nation and announces that he has asked his government to resign. Later in the day he appoints Omar Suleiman, his intelligence chief, as his vice president. Suleiman is Mubarak's first vice president in 30 years of rule.
January 31, 2011 - Swears in his new cabinet.
February 1, 2011 - Mubarak announces he will step down in September when his term ends.
February 11, 2011 - Egyptian Vice President Omar Suleiman makes a televised announcement telling the world that Hosni Mubarak has stepped down as president of Egypt.
February 11, 2011 - The Swiss cabinet freezes all possible assets in Switzerland belonging to Mubarak or his family.
April 12, 2011 - According to an Egyptian military spokesman, Mubarak is admitted to Sharm el-Sheikh International Hospital. Egyptian State TV is reporting that he suffered a heart attack during questioning over possible corruption charges.
April 13, 2011 - Egypt's Justice Ministry announces that Mubarak and sons Gamal and Alaa have been detained by the authorities. The 15-day detention is part of the investigation of the deaths of protesters in Cairo.
April 26, 2011 - Egypt's prosecutor general announces Mubarak will not be moved to a military hospital in Cairo as ordered because the move would be life-threatening.
April 26, 2011 - The prosecutor general's office extends the detention of Mubarak's sons, Gamal and Alaa, another 15 days.
May 8, 2011 - Mubarak's detention is extended another 15 days. This is the his third 15-day detention.
May 13, 2011 - Mubarak's wife Suzanne is ordered held for 15 days. Shortly afterwards she suffers a heart attack and is hospitalized.
May 17, 2011 - Suzanne Mubarak is released on bail after she gives up bank accounts worth $3.4 million and a villa.
May 24, 2011 - The Egyptian general prosecutor's office announces that Mubarak and sons Gamal and Alaa will face trial on charges of corruption and of killing protesters.
May 28, 2011 - Mubarak and two other officials are found guilty of "causing damage to the national economy," and fined more than $90 million for turning off the internet and cell phone service during the unrest that began in January.
May 30, 2011 - Doctors announce Mubarak's heart condition makes him too ill to be jailed while awaiting trial.
June 20, 2011 - Mubarak's lawyer Farid El Deeb announces that Mubarak has stomach cancer. El Deeb also reveals that Mubarak underwent surgery in Germany in June 2010 to have parts of his pancreas, gall bladder and a growth on his small intestines removed.
July 17, 2011 - Mubarak regains consciousness after falling into a coma earlier in the day, a hospital official says.