Oct. 8, 1996 - Armstrong announces the medical findings in a press conference.
Oct. 24, 1996 - He undergoes surgery to remove two cancerous lesions from his brain.
December 1996 - Doctors tell Armstrong he is cancer-free.
1997 - He establishes the Lance Armstrong Foundation to benefit cancer research and cancer patients.
1999 - Armstrong wins his first Tour de France, riding with the U.S. Postal Team.
2000 - Wins the Tour de France for a second consecutive year.
2000 - Publishes book "It's Not About the Bike: My Journey Back to Life."
2001 - Wins the Tour de France for the third time.
2002 - Wins his fourth consecutive Tour de France.
2002 - A 21-month investigation into whether the U.S. Postal Team used performance enhancing drugs during the 2000 Tour de France closes after finding no evidence of illegal drug use.
July 27, 2003 - Armstrong wins his fifth consecutive Tour de France by 61 seconds.
June 15, 2004 - Announces he is suing the author of a book accusing him of taking performance-enhancing drugs.
June 21, 2004 - A Paris court throws out a request by Armstrong for an emergency ruling ordering the publishers of a book detailing suggestions of doping to insert a denial by Armstrong.
July 25, 2004 - Wins his sixth consecutive Tour de France.
April 18, 2005 - Announces that he will retire after competing in the 2005 Tour de France.
July 24, 2005 - Wins his seventh Tour de France.
Dec. 14, 2005 - Armstrong is indicted in an Italian court and is ordered to stand trial for defaming cyclist Filippo Simeoni. Charges are later dropped in April 2006.
May 31, 2006 - A report from the International Cycling Union is released that clears Armstrong's name of doping allegations from 1999.
Sept. 9, 2008 - Announces his return to professional cycling.
March 24, 2009 - Falls along with 15-20 other riders during a race in Spain and breaks his collarbone.