"All ages, all classes, women even more enthusiastic than men," CNN iReporter Dr. Abdel-Maguid Ramzy said of the crowd he joined for four hours in Tahrir Square, many of whom blamed Morsy and the Muslim Brotherhood for Egypt's economic malaise. "They feel betrayed."

One pocket of violence broke out a few blocks from the square, where police erected a barrier of concrete blocks on a street leading to the Interior Ministry and other government buildings.

Young protesters threw rocks over the barrier at officers stationed there, who responded sporadically with tear gas or threw stones themselves.

At least 29 people were treated for cuts, broken bones and birdshot injuries, Health Ministry spokesman Khaled El Khatib said. Six police officers were also hurt in the disorder near Tahrir Square, according to the Interior Ministry.

Egyptian police also fired tear gas to disperse protesters who tried to cross barbed wire outside the presidential palace, which is in the northeast of Cairo, Nile TV reported.