As coordinator for the world's biggest science experiment, Fabiola Gianotti occupies one of the top jobs in science.
Housed in an underground facility straddling the border between France and Switzerland, CERN (the European Organization for Nuclear Research) is the beating heart of modern physics research. A collaboration of 20 member states, it's also where the world wide web was invented in 1989.
After 18 years at CERN, Gianotti became spokesperson and coordinator of the lab's ATLAS experiment, which employs 3000 scientists. Her role -- a democratically elected position -- is to lead the experiment's strategic planning and present its findings to international media.
ATLAS is the largest detector at CERN, used to record collisions between protons accelerated in the 27km Large Hadron Collider, described as "the planet's most powerful human-built microscope".
It's hoped that, by observing these collisions, which replicate conditions straight after the Big Bang, scientists can address such world-changing questions as the origin of mass, the constitution of dark matter, how fundamental forces unify, and whether there are more than three or four dimensions.
After some initial teething problems, the Large Hadron Collider has this year been cranked up to full power, and has delivered more data in April and June than in the whole of 2011.
The experiment has captured the world's imagination, with "Higgsteria" observable on Twitter, where #HiggsRumors became a trending topic on June 20, as enthusiasts anticipated an announcement about the detector's preliminary 2012 results. (It will screen here, on July 4, at 7am GMT).
Scientists at the US Department of Energy's Fermilab in Illinois believe they may also be close to discovering the elusive particle.
In particular, physics nuts hope such experiments will finally prove or refute the existence of a type of particle called the Higgs Boson. If discovered, this particle would confirm currently accepted theories about the structure of the universe.
"I couldn't tell you which (outcome) I would prefer," Gianotti says. "Building a new particle is very nice but also demonstrating that a mechanism that has been proposed as the solution for many years is not the correct one is a major step forward for fundamental science."
"Of course, mankind has made giant steps forward," she says. "However, what we know is really very, very little compared to what we still have to know."
See also: How girl geeks can get the best tech jobs
"It's important we try to do things we love," she adds, but she also advises scientists to be "extremely patient and extremely humble."
Gianotti's career is statistically exceptional. Female scientists are in the minority, accounting for around 30% of Europe's researchers, according to reports by the European Commission and UNESCO.
A European Commission report notes that, although "girls' underachievement in maths has narrowed in all countries and is on the way to disappearing in most of them," girls tend to lose interest in science in their first three years of secondary school, and believe themselves to be worse than boys at physics, even when their grades are not.
In the United States, a report by the National Science Foundation which came to the same conclusion, observed that even girls who are good at maths show less interest in science careers.
This suggests that, for every Gianotti, there are many more who give up. Yet Gianotti has made it to the top of her field, and is involved at the highest levels in historically significant and pioneering work. What went right for her?
Born in Milan, Gianotti was not drawn to science as a girl. She was educated at a "liceo classico," a type of Italian secondary school with an emphasis on art history, literature and ancient languages, and "very little mathematics or physics," she says.
The daughter of a geologist, Gianotti says she grew up with a love of nature and an immense curiosity about the world around her, fueled by "endless" walks in the mountains, when her father would stop to show "a flower or a plant or a little insect."
As a teenager, Gianotti became interested in philosophy, "a discipline that at least asks the fundamental questions," but took the unusual step of choosing to study physics at university.

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