At the same time, Barbara and Tom admire their son-in-law's strength adding that comments on Facebook have helped with the healing.
Tom read to us from Facebook, "Michael Holm posted a photo to Mary Russo Holm's, says I love you. If love could have saved you, you would have lived forever."
We asked Mike what his hope was for the future and for his daughters' future.
"With Katelyn and Amelia so young, you know finding a cure or a genetic solution so that they don't have to go through this with their families would be my ultimate goal, quest," he said.
As for anyone debating whether to be tested for the gene, he said, ""I would go and get tested. At least you can make an informed decision, and not always wonder 'what if?'
Mike does want his daughters to know the truth about their mom's health when they are old enough to understand.
"I'll be able to tell them their mother's story and let them make the decision," he said. "Who knows what kind of technology will be available then? That's 10, 15 years away. Who knows what might be out there?"
In the meantime, his daughters are a constant reminder of the love of his life. They look so much like Mary.
"It's a little tough, Mike said emotionally. "It makes it special...I mean it's her daughters, they're. so much like her...She's here with them, so that's good."
Mike told us the family is hopeful that his wife's story doesn't die with her, that it helps another family make a plan.
He and Mary Holm's family and friends have created a foundation in her name to help families of breast cancer patients. It actually was Mike and Mary's idea when her sister Debbie died of breast cancer. They had planned to create the foundation in Debbie's name but those plans changed with Mary's prognosis.
The first event is a Low Country Boil & BBQ for all ages Saturday, November 16th at the Mandarin Country Club from 5:30pm - 10:30pm. Ticket prices are $20 for adults and $10 for children ages 6 to 10. Kids 5 and under are free. All proceeds benefit the Mary E. Holm Foundation. You can register at maryholm.eventbrite.com.
If you would like to make a donation, you can make checks payable to Mar E. Holm Foundation. Please put attention Terri Bowman. You can send the donation to 3901 Carmichael Avenue, Jacksonville, Florida 32207. For questions you can call (904) 813-6369.