Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and a receiving score, and the San Francisco 49ers beat the sloppy Arizona Cardinals 41-22.

Eddy Piñeiro hit a 41-yard field goal in overtime before San Francisco stopped Kyren Williams on fourth down with 3:36 to play, and the short-handed 49ers hung on for a thrilling 26-23 victory over the Los Angeles Rams.

Atlanta’s Younghoe Koo booted a 41-yard field goal in overtime after the Carolina Panthers missed a pair of kicks that could have won the game.