Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and a receiving score, and the San Francisco 49ers beat the sloppy Arizona Cardinals 41-22.

Two people with knowledge of the penalty say Arizona Cardinals coach Jonathan Gannon has been fined $100,000 by the team after a heated sideline altercation with Emari Demercado following the running back’s costly fumble during the team’s 22-21 loss to the Tennessee Titans.

Arizona Cardinals coach Jonathan Gannon says he apologized to Emari Demercado after a heated sideline conversation following the running back’s costly, unforced fumble.

Cam Ward throws for a career-high 265 yards, leading the Tennessee Titans to a 22-21 victory over the Arizona Cardinals.

Arizona Cardinals running back Emari Demercado had a 72-yard touchdown wiped away against the Tennessee Titans after he tossed the ball before crossing the goal line.

Jason Myers made a 52-yard field goal as time expired, Sam Darnold threw for 242 yards and a touchdown, and the Seattle Seahawks withstood a late rally by Kyler Murray and the Cardinals to beat Arizona 23-20.

Emari Demercado ran 53 yards for a touchdown just before halftime, James Conner added 107 yards on the ground and the surging Arizona Cardinals put together a dominant 29-9 victory over the Chicago Bears on Sunday.