Brock Purdy threw a career-high five touchdown passes and Dee Winters returned an interception 74 yards for a score to lead the San Francisco 49ers to a 48-27 victory at Indianapolis.
Carolina Panthers safety Tre’von Moehrig has been suspended one game without pay for punching San Francisco 49ers wide receiver Jauan Jennings in the groin during Monday’s game.
San Francisco receiver Jauan Jennings responded to a cheap shot from Carolina safety Tre'Von Moehrig by throwing a punch after the final whistle.
Four-time All-Pro linebacker Fred Warner will need season-ending surgery after he was sidelined by a severe ankle injury during San Francisco's loss to Tampa Bay.
San Francisco star defensive end Nick Bosa tore the ACL in his right knee and will miss the rest of the season.
Quarterback Brock Purdy is highly unlikely to start for the San Francisco 49ers on Sunday because of a toe injury.
San Francisco 49ers quarterback Brock Purdy is a "long shot" to play against the New Orleans Saints on Sunday due to a toe injury.
Christian McCaffrey has been a standout at the San Francisco 49ers' training camp, remaining healthy after missing most of last season because of injuries.
The San Francisco 49ers have given receiver Deebo Samuel permission to seek a trade, according to a person familiar with the situation.
Joshua Karty hit a 37-yard field goal with 2 seconds to play, and the Los Angeles Rams staged a spectacular late rally for a 27-24 victory over the San Francisco 49ers.
Jauan Jennings’ historic Super Bowl milestone will turn into only a footnote after his San Francisco 49ers lost the game.
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