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Four-time Grand Slam champion Naomi Osaka has lost in the first round of a second consecutive major tournament.
Serena Williams has lost her first singles match in nearly a year.
Rafael Nadal reached 300 career Grand Slam match victories by beating Corentin Moutet 6-3, 6-1, 6-4 in the second round of the French Open at Roland Garros.
Once is enough when it comes to beating Rafael Nadal on a clay court.
John Isner believes in his chances against Rafael Nadal in the second round of the Italian Open.