Jacksonville detectives have investigated more than 220 overdose deaths in 2025 and have arrested 17 drug dealers on manslaughter charges in connection with some of those cases, Sheriff T.K. Waters announced Tuesday.

A 48-year-old Palm Coast woman has been charged with manslaughter in connection with the overdose death of 22-year-old Calvin Stull, whose body was discovered in Belle Terre Park just over one year ago.

To get an inside look, the News4JAX I-TEAM embedded with JSO’s Overdose Squad, made up of detectives from both homicide and narcotics, responding to some of the calls with them.

Drug-related deaths are down in Florida, according to a new report from the Florida Department of Law Enforcement.

Of those with chronic pain in the U.S., up to 30% misuse opioids -- that means millions are living in a vicious cycle of pain and addiction. An implant may help relieve their pain without drugs.

The White House has launched a new national online database, which tracks the rates of nonfatal opioid overdoses. That website went live just yesterday -- and officials say the goal is to help direct resources to the areas where they're needed the most.

Jacksonville Fire and Rescue paramedics are seeing hundreds of overdose cases every month among the many calls they respond to.

A fugitive found in Flagler County faces charges after deputies say he had 200 grams of fentanyl, which is enough to potentially kill 100,000 people.

A St. Augustine mom is speaking up about fentanyl deaths after her daughter died in May from being unknowingly exposed to the deadly drug.

The Drug Enforcement Administration has issued a nationwide warning over what it’s referring to as “rainbow fentanyl,” which as the name implies, is brightly colored and appears to resemble hard candy.

Last year the Drug Enforcement Administration seized 20 million fake pills and four out of 10 of those pills that had fentanyl contained a potentially lethal dose.

For 10 years, a Clay County man took so many prescription pills that he almost died the day his wife found him unconscious on their living room floor. Today, Matthan Poole is a local pastor, and he and his wife, Sara, are using his near-death experience to bring others hope.

Project Opioid Jax presented staggering data Wednesday about the opioid crisis in Jacksonville during a news conference on International Overdose Awareness Day.

Aug. 31 is Overdose Awareness Day, and News4JAX is teaming up with local organizations hoping to save lives. The main culprit behind the surge in overdose cases, locally, is fentanyl.

As we continue to shed light on the overdose epidemic, we want to make sure you know that you can make a difference and save a life by arming yourself with an overdose-reversing medication.

Aug. 31 is Overdose Awareness Day, and News4JAX is teaming up with local organizations hoping to save lives. The main culprit behind the surge in overdose cases we’re seeing in our area is fentanyl.

The head of the Food and Drug Administration says a government review of prescription opioid medications, including their risks and contribution to the U.S. overdose epidemic, is still underway.