AZEEZ AL-SHAAIR

Jimmy Garoppolo injured his right thumb in San Francisco’s loss at Tennessee last week and his status for the 49ers’ game this week is in doubt.

Jimmy Garoppolo threw a 12-yard touchdown pass to Brandon Aiyuk and the San Francisco 49ers beat the Cincinnati Bengals 26-23 in overtime.

The Jaguars have already pulled one major upset this season when they beat the Bills. Is another shocker in store? Here’s what Jacksonville needs to do to emerge with its third win of the season.

There are many words that I would use to describe how the Jaguars' offense has looked but speed is not one of them.

Jimmy Garoppolo threw two touchdown passes for the third consecutive week and the San Francisco 49ers dominated Jacksonville 30-10 on Sunday for their third win in four games.

___10:09 p.mArizona Cardinals linebacker Isaiah Irving has been carted off the field after a collision on a kickoff just before halftime against the Seattle Seahawks. Jacksonville rallied from a 16-0 deficit and took the lead, but the Jaguars have been blanked in the fourth quarter. ___7:10 p.m.Tom Brady moved one touchdown pass ahead of Drew Brees for the career lead. Mayfield threw a 3-yard touchdown pass to Harrison Bryant to even the score in the second quarter. New York leads 3-0.

(AP Photo/Jed Jacobsohn)SANTA CLARA, Calif. – Carson Wentz hit Travis Fulgham on a 42-yard touchdown pass with 5:50 remaining to lift the Philadelphia Eagles to their first win of the season, 25-20 over the San Francisco 49ers on Sunday night. TAKE IT AWAYThe Eagles got their first defensive takeaway of the season thanks to a poor decision by Mullens. With the Niners in the red zone, Mullens threw a ball up for grabs while under pressure and Rodney McLeod came up with it. INJURY REPORTEagles: RT Lane Johnson left the game in the first half with an ankle injury but later returned. 49ers: DL Ezekiel Ansah left the game in the first half with an arm injury and didn’t return.